Alternative survival pathways are commonly seen to be upregulated upon inhibition of receptor tyrosine kinases (RTK), including Her-2.It is established that treatment with Herceptin leads to selective overexpression and activation of epidermal growth factor Pedestal Fans receptor (EGFR) and Src which further contributes to oncogenesis in Herceptin
The article presents the problems of determining the mass efficiency of a rotary feeder depending on the selection of design parameters of the device, such as outer diameter, number of blades and rotational speed of the rotor.The hitherto theoretical methods of calculating the feeder efficiency were presented, as well as a new method of determining
Restraint and cold stress increase both corticosterone and glycemia, which lead to oxidative damages in hepatic tissue.This study assessed the effect of royal jelly (RJ) supplementation on the corticosterone level, glycemia, plasma enzymes and hepatic antioxidant system in restraint and cold stressed rats.Wistar rats were allocated into no-stress,